Last update
3/19/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc picolinate)
22 mg
200%
Top Medical Research Studies
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
Most Useful Reviews
9
Reliable supplement choice.
9 people found this helpful
As usual, Solgar provides high-quality supplements that I can trust. I take the Zinc Picolinate daily due to being on birth control pills, which deplete certain nutrients. This zinc has greatly improved my skin.
Read More
7.5
Hair loss improvement.
1 people found this helpful
Great! I completed the course of Solgar zinc some time ago, and I must share my impressions. Zinc is essential for keeping skin and hair healthy. It enhances skin condition by regulating sebaceous glands, bolsters the immune system, prevents inflammation, and supports healing. I particularly needed it as I was experiencing significant hair loss. After several weeks, without much faith, I noticed my hair falling out less and my skin appearing healthier. I plan to continue taking it.
Read More
7.5
Supports immune system well.
4 people found this helpful
Wonderful! My skin condition has greatly improved. This highly absorbable zinc picolinate helps offset my magnesium deficiency. I take one tablet daily with meals, and it supports my immune system well. It's important to monitor copper levels while taking zinc. Delivery was swift, arriving in 10 days.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Read More
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Read More
8
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
Read More
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
Read More
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reliable supplement choice.
9 people found this helpful
As usual, Solgar provides high-quality supplements that I can trust. I take the Zinc Picolinate daily due to being on birth control pills, which deplete certain nutrients. This zinc has greatly improved my skin.
Read More
7.5
Hair loss improvement.
1 people found this helpful
Great! I completed the course of Solgar zinc some time ago, and I must share my impressions. Zinc is essential for keeping skin and hair healthy. It enhances skin condition by regulating sebaceous glands, bolsters the immune system, prevents inflammation, and supports healing. I particularly needed it as I was experiencing significant hair loss. After several weeks, without much faith, I noticed my hair falling out less and my skin appearing healthier. I plan to continue taking it.
Read More
7.5
Supports immune system well.
4 people found this helpful
Wonderful! My skin condition has greatly improved. This highly absorbable zinc picolinate helps offset my magnesium deficiency. I take one tablet daily with meals, and it supports my immune system well. It's important to monitor copper levels while taking zinc. Delivery was swift, arriving in 10 days.
Read More
7.5
Boosts immunity
1 people found this helpful
The quality is superior, as the zinc is in a balanced form, enhancing the immune system after completing the course. My hair has ceased to fall out. The package contains enough for several family members.
Read More
7.5
Fewer rashes observed.
21 people found this helpful
My daughter has teenage rashes, so we took zinc picolinate, opting for Solgar due to the high quality of their vitamins and our trust in the brand. We take it at lunch alongside vitamin A and a probiotic while improving her diet by removing sweets. We see fewer rashes, and when they do appear, they are minor and heal quickly. I highly recommend this product. If this review was helpful, please like!
Read More
Frequently Asked Questions
7.5
Hair loss improvement.
1 people found this helpful
Great! I completed the course of Solgar zinc some time ago, and I must share my impressions. Zinc is essential for keeping skin and hair healthy. It enhances skin condition by regulating sebaceous glands, bolsters the immune system, prevents inflammation, and supports healing. I particularly needed it as I was experiencing significant hair loss. After several weeks, without much faith, I noticed my hair falling out less and my skin appearing healthier. I plan to continue taking it.
7.5
Fewer rashes observed.
21 people found this helpful
My daughter has teenage rashes, so we took zinc picolinate, opting for Solgar due to the high quality of their vitamins and our trust in the brand. We take it at lunch alongside vitamin A and a probiotic while improving her diet by removing sweets. We see fewer rashes, and when they do appear, they are minor and heal quickly. I highly recommend this product. If this review was helpful, please like!
0
Negative hair effects
1 people found this helpful
Be cautious! My hair began falling out due to this zinc—everywhere, from my legs to my head. My mother experienced the same issue. While there may be some good skin benefits, the price is rather exorbitant, considering the hair loss.
We explored how zinc supplementation affects cholesterol levels and body composition in patients with type 2 diabetes. By reviewing data from nineteen randomized controlled trials, involving 1,357 participants, we uncovered significant findings regarding lipid profiles.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
Our results revealed that zinc supplementation leads to reduced levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol (LDL-C). Specifically, we noted reductions of 17.41 mg/dL in triglycerides, 19.60 mg/dL in total cholesterol, and 8.80 mg/dL in LDL-C. Furthermore, we observed an increase in high-density lipoprotein cholesterol (HDL-C) by 4.82 mg/dL, which is often termed "good" cholesterol.
While zinc appears to positively influence cholesterol levels, it's interesting to note that it did not have a significant impact on body weight. The body mass index (BMI) did show a slight decrease of 0.53 kg/m², but overall body weight remained unchanged.
In conclusion, our findings suggest that zinc supplementation could be a beneficial strategy for improving cholesterol levels in individuals with type 2 diabetes, thus contributing positively to their overall health and well-being.
8
We delved into the intriguing relationship between trace minerals, specifically zinc, and high cholesterol levels related to coronary artery disease (CAD). Our study focused on middle-aged and older adults living in Shika town, Japan, and involved 895 residents, carefully excluding those with a genetic predisposition to high cholesterol.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
By analyzing their dietary habits through a questionnaire, we found notable interactions between dyslipidaemia, or high cholesterol, and zinc intake. Our detailed examination revealed that a lower intake of zinc, alongside other trace minerals like copper and manganese, correlated with a higher risk of CAD in individuals with dyslipidaemia.
What we learned was striking: zinc, copper, and manganese emerged as significant factors linked to CAD, especially for those struggling with dyslipidaemia. The odds ratios suggested that sufficient zinc intake might play a protective role against CAD in these individuals. These findings illuminate the potential importance of trace minerals in maintaining heart health, particularly for those facing challenges with cholesterol levels. However, further research is essential to confirm these early observations and better understand the nature of these relationships.
7
Zinc's role in cholesterol management
In our study, we explored how zinc supplementation might influence cholesterol levels in a controlled experiment with male Wistar rats. We divided the 48 rats into three diet groups: those on a high-fat diet, a caloric restriction diet, and a normal diet. The high-fat diet group was further split into four categories, where some received zinc, selenium, or a combination of both, while one group served as the control.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
After eight weeks of monitoring, we conducted biochemical tests to assess key factors such as triglyceride levels, cholesterol, and blood sugar. Although zinc has potential benefits, our findings suggest that its supplementation did not significantly lower cholesterol levels when compared to the control group on a high-fat diet. Despite the lack of notable changes, this research indicates that more studies are needed to understand zinc's role in managing high cholesterol, especially when combined with other supplements.
We came to realize that while zinc and selenium have their merits, they might not directly target high cholesterol levels effectively within this specific model. The complexity of obesity-related conditions requires a deeper investigation into individual nutrient effects and their interactions.
8
Study on zinc and cholesterol outcomes
We conducted a randomized clinical trial involving 75 patients with type 2 diabetes to explore the effects of a nutraceutical combination containing myo-inositol, d-chiro-inositol, α-lactalbumin, Gymnema sylvestre, and zinc on cholesterol levels.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
While the overall results showed no significant improvement in glucose levels among the groups, we did observe reductions in total cholesterol and LDL levels in the supplement group after three months. Interestingly, a subgroup that did not change their diabetes medication displayed even greater improvements in cholesterol levels—suggesting potential benefits from the supplement combination.
However, it's important to note that the study did not assess the specific impact of zinc alone on cholesterol. Therefore, while we found promising results for the combination used, we cannot definitively attribute any cholesterol-lowering effects directly to zinc in isolation.
8
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
References
- Chhina GS, Chhabra A, Luthra SR, Khattar S, Singh P, et al. Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus. Cureus. 2024;16:e69180. 10.7759/cureus.69180
- Kimura K, Suzuki F, Tsujiguchi H, Hara A, Miyagi S, et al. Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study. J Nutr Sci. 2024;13:e45. 10.1017/jns.2024.26
- Hasani M, Monfared V, Aleebrahim-Dehkordi E, Jafari A, Agh F, et al. The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats. Curr Mol Med. 2024;24:1307. 10.2174/0115665240268180231113045836
- Khajeh M, Hassanizadeh S, Pourteymour Fard Tabrizi F, Hassanizadeh R, Vajdi M, et al. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis. Biol Trace Elem Res. 2024;202:4877. 10.1007/s12011-024-04059-x
- Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. 10.3390/jcm12247650
Data last updated:
